At Exhalix we are applying our experience in developing trace-level gas sensors, microfluidic systems, and microelectronic devices to develop breakthrough medical diagnostic and therapeutic products. We have partnered with leading research organizations uncovering the roles of Hydrogen Sulfide (H2S) in human physiology and its applications in disease diagnosis and therapy.
Hydrogen Sulfide Gastrotransmitter, Biomarker, Therapeutic Agent
Why is H2S Important?
Sometimes referred to as the third gasotransmitter, after Nitric Oxide (NO) and Carbon Monoxide (CO), Hydrogen Sulfide (H2S) has been shown to play a significant role in human physiology and pathophysiology. Generated endogenously, normal levels of H2S regulate organ development and maintain homeostasis, while abnormal levels are associated with many cardiovascular and neurodegenerative diseases. In recent years, the research into H2S as a diagnostic biomarker and a therapeutic agent has increased substantially.
Endothelial Dysfunction Diagnosis, Therapy
Among many applications of H2S in medicine, Exhalix is currently focused the application of our Transdermal Arterial Gasotransmitter Sensor (TAGS™) on early detection of microvascular and Peripheral Artery Disease (PAD) and improving prognosis of Critical Limb Threatening Ischemia (CLTI) treatment. We are also working on combining trace-level transdermal H2S detection with local administration of H2S donors to develop active wound dressings that greatly improve outcomes for hard to heal chronic and surgical wounds.
Develop highly effective and widely adopted medical devices for diagnosis, prevention, and treatment of peripheral vascular disease and its complications.